MyBioSource.com's ALOXE3 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The ALOXE3 Antibody (Center) was generated using ALOXE3, and E-LOX as the antigen and it reacts with Human, and Mouse.
Description
ALOXE3 is a member of the lipoxygenase family, which
are catabolized by arachidonic acid-derived compounds. The encoded
enzyme is a hydroperoxide isomerase that synthesizes a unique type
of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic
acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This
epoxy alcohol can activate the the nuclear receptor peroxisome
proliferator-activated receptor alpha (PPARalpha), which is
implicated in epidermal differentiation. Loss of function of the
enzyme encoded by this gene results in ichthyosis, implicating the
function of this gene in the differentiation of human skin